Treatment of Malignant Mesothelioma: Extrapleural Pneumonectomy with Intraoperative Chemotherapy

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Extrapleural pneumonectomy in malignant pleural mesothelioma.

Standard treatment for malignant pleural mesothelioma (MPM) has not been proved yet. However, it has been recognized that extrapleural pneumonectomy (EPP) is a treatment of choice for epithelial MPM when combined with adjuvant therapies though EPP may frequently cause fetal complications. We report 5 cases of MPM with EPP, including 1 with good prognosis. Sixteen patients with MPM were admitted...

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Video-assisted thoracoscopic extrapleural pneumonectomy for malignant pleural mesothelioma.

Ann Cardiothorac Surg 2012;1(4):533 www.annalscts.com This video demonstration represents our first attempt at video-assisted thoracoscopic extrapleural pneumonectomy (EPP) for a 51-year-old patient with right-sided malignant pleural mesothelioma following neoadjuvant chemotherapy (Video 1). While originating as an initial inspection for a possible radical decortication, it was apparent that th...

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Extrapleural pneumonectomy for malignant mesothelioma: an Italian multicenter retrospective study.

BACKGROUND This study assessed perioperative outcome and long-term survival in a large series of patients with malignant pleural mesothelioma who underwent extrapleural pneumonectomy (EPP) to identify prognostic factors allowing better patient selection. METHODS We retrospectively collected data from nine referral centers for thoracic surgery in Italy. Perioperative outcome and survival data ...

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Extrapleural pneumonectomy or pleurectomy/decortication for malignant pleural mesothelioma

Malignant pleural mesothelioma (MPM) is associated with a very poor prognosis. Unlike other solid tumors, any type of planned surgery for MPM would be cytoreductive rather than radical. There are two types of surgery for MPM. Extrapleural pneumonectomy (EPP) involves en bloc resection of the lung, pleura, pericardium, and diaphragm. Pleurectomy/decortication (P/D) is a lung-sparing surgery that...

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Multicenter trial of neo-adjuvant chemotherapy followed by extrapleural pneumonectomy in malignant pleural mesothelioma.

BACKGROUND The aim of this multicenter trial was to prospectively evaluate neo-adjuvant chemotherapy followed by extrapleural pneumonectomy (EPP) and radiotherapy, including quality of life as outcome. PATIENTS AND METHODS Eligible patients had malignant pleural mesothelioma of all histological types, World Health Organization performance status of zero to two and clinical stage T1-T3, N0-2, ...

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ژورنال

عنوان ژورنال: Operative Techniques in Thoracic and Cardiovascular Surgery

سال: 2006

ISSN: 1522-2942

DOI: 10.1053/j.optechstcvs.2006.02.001